Inflammation

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Inflammation Objectives

Outline each step of inflammation, including why it is an important process and the role of white blood cells.
List different inflammatory diseases that have appeared throughout this course.
Match different forms of visualization with the information that is being conveyed.

Innate inflammation and the two acquired forms of immunity (cell-mediated and antibody-mediated) involve white blood cells. This video recalls the five basic types of wbcs.

The role of white blood cells in the inflammation is discussed in the next two videos.

For the quiz question from this page, you will be asked to explain each step of inflammation from wounded cells to clean-up by the white blood cells. You can submit a written story response, but many people prefer to make a labeled sketch. You can work on either of these while watching the videos.

This poster summarizes the non-specific defenses of barriers and inflammation. It also adds antimicrobial proteins that are often released during inflammation responses.

Wounded cells secrete chemicals that start the inflammation response. Vessels dilate, blood flushes out the wound, platelets form a clot, and the white blood cells arrive.

Natural Killer lymphocytes, the same type that kill cancer cells, start killing damaged cells, leaving room for new, healthy cells to take their place.

Neutrophils become phagocytes which means “eating cells,” and they eat up the debris, including the mess left by the natural killer cells.

Monocytes turn into macrophages or “big eaters,” and they eat up the large debris the neutrophils can’t handle. Monocytes also play a role in both types of specific immunity.

Which suffix is added to a word to indicate an inflammatory disease? -____

List as many inflammatory diseases as you can remember from the course so far. There have been quite a few!

Inflammation is an important process, but as we have seen throughout this course, many diseases are related to excessive and chronic inflammation.

Communicating scientific knowledge clearly and accurately relies on effective use of visuals. In one of next week’s media assignments, you will be creating a form of visualization that conveys information from the body data you have been collecting.

Data visualization is the use of graphs, plots, infographics, and other figures to visually represent data.

Data visualization starts with a choice: selecting the correct format to represent the data accurately.

Advance through this slider to review eight common forms of data visualization, and what they represent.

Hover over the images to pause the scroll

Time Series
A single variable is captured over a period of time. A line is often used to connect the data, showing trends in the variable over time.
Correlation
This compares two variables (X,Y) and shows whether they move in the same or opposite directions. A scatterplot is often used for correlative data.
Ranking
The categories are ranked in an ascending or descending order. A bar chart is often used. This is not continuous data like a line chart, but data representing different collection intervals, with no assumption of linearity between the bars.
Part to a Whole
Divided parts are compared to a larger whole. A pie chart is frequently used to show percentages.
Deviation
A comparison of the actual data to a reference. Bar charts are often used to show the deviation of the real from expected data.
Frequency Distribution
Provides the number of a variable at an interval, typically a time interval. A histogram is often used for displaying this data.
Nominal Comparison
This represents categories that are not in a particular order. Bar charts are often used, and there is no assumed relationship between the different bars,
Geospatial
A variable is located on a map or layout, the visualization is called a cartogram.

Once you have selected a type of figure that accurately represents the data, it is time to add information to make sure the figure is clear and easy to read.

Labels provide critical information on what is included in a figure.

This typically includes a title, labeled axes, and a key of any lines, bars, dots, or other data represented in the chart in which the meaning is not obvious.

Line, colors, textures, and patterns can distinguish between different forms of data.

It is important to minimize information that may distract from the data or lead to misconceptions.

Now, the data visualization needs to be engaging: capturing and holding the viewer’s attention so they will read and think about the figure.

This video presents the idea of making data visualizations engaging to a reader.

People will not look for information within data, or convert that information into knowledge and usable wisdom, unless the data is presented in an accurate, clear, and compelling manner.

The next section introduces cell-mediated immunity, an acquired and specific defense against pathogens.

Check your knowledge. Can you:

outline each step of inflammation, including why it is an important process and the role of white blood cells?
list different inflammatory diseases that have appeared throughout this course?
match different forms of visualization with the information that is being conveyed?

Go back to the Defenses Overview & Barriers Page

Inflammation

Inflammation Objectives

The role of white blood cells in the inflammation is discussed in the next two videos.

For the quiz question from this page, you will be asked to explain each step of inflammation from wounded cells to clean-up by the white blood cells. You can submit a written story response, but many people prefer to make a labeled sketch. You can work on either of these while watching the videos.

Which suffix is added to a word to indicate an inflammatory disease? -____

List as many inflammatory diseases as you can remember from the course so far. There have been quite a few!

Communicating scientific knowledge clearly and accurately relies on effective use of visuals. In one of next week’s media assignments, you will be creating a form of visualization that conveys information from the body data you have been collecting.

Advance through this slider to review eight common forms of data visualization, and what they represent.

Hover over the images to pause the scroll

Time Series

Correlation

Ranking

Part to a Whole

Deviation

Frequency Distribution

Nominal Comparison

Geospatial

Once you have selected a type of figure that accurately represents the data, it is time to add information to make sure the figure is clear and easy to read.

Now, the data visualization needs to be engaging: capturing and holding the viewer’s attention so they will read and think about the figure.

The next section introduces cell-mediated immunity, an acquired and specific defense against pathogens.

Check your knowledge. Can you:

Go back to the Defenses Overview & Barriers Page

Go forward to the Cell-Mediated Immunity Page

Defense Systems Lecture Guide Contents

The material from this guide and corresponding lecture is assessed on the weekly quiz.

Overview & Barriers

Inflammation - YOU ARE HERE

Cell-Mediated

Antibody-Mediated

Back to Module 9

This week’s overview

This Guide

Defense Systems

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